Ask a Librarian: COVID-19 (updated regularly)

Testing for COVID-19

Last updated: November 23, 2020 - Originally published: February 10, 2020

Did you know CMA members have access to skilled medical librarians? Our team of librarians can support you by searching on your behalf, teaching you effective search strategies or training you to use our resources. You’re getting the latest evidence and saving time, so you can focus on what’s important to you.

 

Joule’s Ask a Librarian team has committed its skills to curate free evidence-based resources related to the current COVID-19 pandemic. This page will be updated regularly – the information and resources added most recently will be marked with an asterisk (*).

Visit the CMA’s COVID-19 page for the latest public health information and resources for physicians and patients. 

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Clinical summaries

DynaMed

Access DynaMed online or through the mobile app to get concise overviews and detailed recommendations, medical graphics and images, drug information from Micromedex and more.

COVID-19 (Novel Coronavirus) – Updated Nov 13, 2020

Description

  • global pandemic of acute respiratory disease caused by a novel coronavirus (SARS-CoV-2) 1
  • SARS-CoV-2 is a member of beta genus coronaviruses closely related to SARS-CoV (Nat Microbiol 2020 Mar 2 early online)
  • common signs of COVID-19 include fever, cough, and shortness of breath1
  • there is no specific antiviral treatment for COVID-19, but supportive care may help to relieve symptoms and should include support of vital organ functions in severe cases1

Recent updates *

  • 13 Nov 2020: FDA alerts health care providers about false positive results with antigen tests used for rapid detection of SARS-CoV-2 and issues recommendations to limit false positive or false negative results (FDA Letter to Health Care Providers 2020 Nov 03) View in topic
  • 12 Nov 2020: in-hospital mortality 28% in adults admitted to ICU with severe COVID-19 up to August 2020 (Chest 2020 Oct 15 early online) View in topic
  • 12 Nov 2020: 45%-56% mortality reported in adults with COVID-19 who received invasive mechanical ventilation (Am J Respir Crit Care Med 2020 Oct 29) View in topic
  • 11 Nov 2020: tocilizumab might not prevent clinical worsening at 14 days in adults hospitalized with COVID-19 pneumonia (JAMA Intern Med 2020 Oct 20 early online) View in topic
  • 11 Nov 2020: addition of tocilizumab to usual care might decrease risk of composite of death and need for noninvasive or mechanical ventilation on day 14 in adults hospitalized with moderate-to-severe COVID-19 pneumonia (JAMA Intern Med 2020 Oct 20 early online) View in topic
  • 10 Nov 2020: chest CT appears to have sensitivity about 85% but very low specificity for diagnosing COVID-19 in patients with suspected COVID-19 (Cochrane Database Syst Rev 2020 Sep 30) View in topic

Topic Summary (CMA members can access all full summaries via this link)

DynaMed COVID-19 related summaries

BMJ Best Practice

Coronavirus disease 2019 (COVID-19) – Last reviewed October 17, 2020. This topic last updated: November 17, 2020.

 

UpToDate

Coronavirus disease 2019 (COVID-19) – Literature review current through October 2020. This topic last updated: November 16, 2020.

 

Essential Evidence Plus

Coronavirus SARS-CoV2 infection (COVID-19) – This topic last updated: September 28, 2020.

 

Canadian Pharmacists Association

COVID-19 – Information for primary care practitioners on the management of common symptoms and a summary of experimental treatments being used in acute-care settings. This topic last updated: June 25, 2020.

 

Clinical information via ClinicalKey

ClinicalKey drives better care by delivering fast, concise answers, and deep access to evidence whenever, wherever you need it. ClinicalKey includes access to 1,000+ textbooks, 600 full-text journals, images, videos and customizable patient handouts across 30+ medical specialties

Novel Coronavirus Information Center  (Elsevier/ClinicalKey) - freely available and current information in English and Mandarin Chinese. Updated: November 16, 2020.

In ClinicalKey (CMA members only), search “COVID-19” for the latest articles from The Lancet, International Journal of Infectious Diseases, Journal of Infection and more.

Procedural Videos - Orotracheal Intubation (login required).

Book chapters:

Gerber  Novel Coronavirus from Wuhan China, 2019-20, Update to Chapter 155, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, Ninth Edition (Elsevier, 2020). 

Coronaviruses, Including Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS), Chapter 155, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, Ninth Edition (Elsevier, 2020).

 

Evidence syntheses *

CADTH COVID-19 evidence portal – Canadian Agency for Drugs and Technologies in Health. Updated October 9, 2020. Accessed November 17, 2020.

Centre for Evidence-Based Medicine Oxford University – COVID-19 evidence service. Accessed November 17, 2020.

Coronavirus Disease 2019 (COVID-19) Daily Research Briefs – American Family Physician. Updated November 16, 2020. Accessed November 18, 2020. *

COVID-19: a living systematic map of the evidence - EPPI Centre. Updated October 8, 2020. Accessed November 17, 2020.

COVID-19 Evidence Alerts – weekly update of high-quality clinical studies curated by McMaster University. Free email notification is available upon registration. Last updated November 17, 2020. Accessed November 17, 2020.

COVID-19 Evidence Network to support Decision-making (COVID-END) – McMaster University – No date. Accessed November 17, 2020.

COVID-19 Evidence Reviews – VA Evidence Synthesis Program. Updated November 16, 2020. Accessed November 17, 2020.

COVID-19 research briefs - Essential Evidence Plus – Joule, A CMA Company. Updated November 15, 2020. Accessed November 17, 2020. *

Evidence aid ‒ Coronavirus (COVID-19) – summaries of relevant research. Updated November 13 2020. Accessed November 17, 2020.

REAL – COVID-19 Rapid Evidence Resource Link – Dala Lana School of Public Health – University of Toronto. Updated November 11, 2020. Accessed November 17, 2020.

 

Articles, article collections and reviews

Annals of Internal Medicine - Coronavirus Disease 2019 (COVID-19).

BMJ - Coronavirus (COVID-19) hub – collection of freely available news articles, opinion and timeline.

Cambridge University Press – Coronavirus Free Access Collection. 

CMAJ – COVID-19 – CMAJ articles, podcasts and blogs on public health and policy.

Epocrates COVID-19 Drug Therapy Trial Updates – links to trials and resources focused on therapeutics. 

JAMA Coronavirus Disease 2019 (COVID-19) – collection of current articles and multimedia.

The Lancet COVID-19 Resource Centre – free access to COVID-19 content from across The Lancet journals.

Merck Manuals COVID-19 Information and Resources – news, commentary and FAQs.

New England Journal of Medicine – Coronavirus (COVID-19) – collection of articles and other resources on the 2019 Novel Coronavirus outbreak including clinical reports, management guidelines and commentary (Chinese translations available for some content).

Oxford University Press – free access to OUP resources on COVID-19, other coronaviruses and related topics. 

Springer-Nature - Coronavirus  (COVID-19) Research Highlights. 

Wiley Online Library - Covid-19: Novel Coronavirus Outbreak. 

Wolters Kluwer COVID-19 Resources & Tools (Coronavirus Resources) – updates and articles. 

 

Guidelines and other information

International 

Coronavirus (COVID-19) – National Institute for Health and Care Excellence (UK). No date.  Accessed November 17, 2020.

Caring for people with COVID-19 – National COVID-19 Clinical Evidence Taskforce (Australia). Last updated November 12, 2020. Accessed November 17, 2020. 

Coronavirus Disease 2019 (COVID-19): information for health care professionals – Centers for Disease Control and Prevention. Last reviewed August 25, 2020. Accessed November 17, 2020. 

Interactive, global map tracking COVID-19 – Johns Hopkins University. Updated November 17, 2020. Accessed November 17, 2020.

Coronavirus disease (COVID-19) pandemic – World Health Organization. Updated November 16, 2020. Accessed November 17, 2020.

Coronavirus disease - European Centre for Disease Prevention and Control. Updated November 17, 2020. Accessed November 17, 2020. 

Penn Medicine COVID-19  Guidance Summaries - University of Pennsylvania Center for Evidence-based Practice. Updated July 27, 2020. Accessed November 17, 2020.

Global Coronavirus COVID-19 Clinical Trial Tracker - world map of clinical trials. Last updated November 16, 2020. Accessed November 17, 2020. 

 

National

Clinical guideline search (CPG Infobase) – Joule, A Canadian Medical Association Company. Clinical Practice Guidelines on COVID-19/Coronavirus infections. Updated November 17, 2020. Accessed November 17, 2020.

CMA update: COVID-19 – Canadian Medical Association No date. Accessed November 17, 2020.

COVID-19 – Choosing Wisely Canada. Last updated April 30, 2020. Accessed November 17, 2020.

COVID-19 A data perspective – Statistics Canada. Last updated November 17, 2020. Accessed November 17, 2020.

COVID-19 Information and Resources – College of Family Physicians of Canada. No date. Accessed November 17, 2020.

COVID-19 Resource Centre  – The Centre for Effective Practice. Updated September 2020.  Accessed November 17, 2020.

Coronavirus disease (COVID-19): Outbreak update – Government of Canada. Updated November 16, 2020. Accessed November 17, 2020.

Coronavirus disease (COVID-19): For health professionals – Government of Canada. Updated November 9, 2020. Accessed November 17, 2020.

Coronavirus infection: Symptoms and treatment – Government of Canada. Updated November 17, 2020. Accessed November 17, 2020.

Coronavirus (COVID-19) SARS-CoV-2 – Infection Prevention and Control Canada. Updated November 13, 2020. Accessed November 17, 2020.

Infection prevention and control for coronavirus disease (COVID-19): Second interim guidance for acute healthcare settings  – Public Health Agency of Canada. Updated May 19, 2020. Accessed November 17, 2020.

 

Provincial

British Columbia:

Yukon: COVID-19 information  – Government of Yukon. Updated November 17, 2020.  Accessed November 17, 2020.

Northwest Territories: COVID-19 in NWT – Government of Northwest Territories – Health and Social Services. Updated November 16, 2020. Accessed November 17, 2020.

Alberta: Novel Coronavirus (COVID-19) – Alberta Health Services. Updated November 16, 2020. Accessed November 17, 2020.

Saskatchewan: COVID-19 – Saskatchewan. No date. Accessed November 17, 2020.

Manitoba: 

Nunavut: COVID-19 (Novel Coronavirus) – Nunavut Department of Health. Updated November 16, 2020.  Accessed November 17, 2020.

Ontario:

Quebec: 

New Brunswick:  Coronavirus – Office of the Chief Medical Officer of Health (Public Health) New Brunswick. No date. Accessed November 18, 2020.

Nova Scotia: 

Prince Edward Island: COVID-19 – Prince Edward Island Health and Wellness. No Date. Accessed November 18, 2020. 

Newfoundland: NLife with COVID-19  – Newfoundland Health and Community Services. Updated November 12, 2020. Accessed November 18, 2020.  

 

Webinars and podcasts 

BMJ Best Practice Podcasts – BMJ Best Practice – No date. Accessed November 18, 2020.

Coronavirus (COVID19) – American Medical Association ED Hub. No date. Accessed November 18, 2020.

TEACH. ENGAGE. APPLY (CUPA-TEA) COVID-10 webinar series - Association of Medical Microbiology and Infectious Disease (AMMI) Canada – Updated November 5, 2020. Accessed November 18, 2020.

COVID-19 Podcasts – CMAJ Podcasts. No date. Accessed November 18, 2020.

COVID-19 Podcasts and Webinars - Center for Infectious Disease Research and Policy, University of Minnesota. Updated November 12, 2020. Accessed November 18, 2020.

COVID-19 Webinars – College of Family Physician of Canada. October 22, 2020. Accessed November 18, 2020.

Clinical Management Through COVID-19 Webinar Series Recordings – Harvard Medical School. Updated November 2, 2020. Accessed November 18, 2020.

Coronavirus videos – The JAMA Network. Updated November 16, 2020. Accessed November 18, 2020.

Joule COVID-19 Learning Series – Joule, A Canadian Medical Association Company – No date. Accessed November 18, 2020.

What’s Next COVID-19 Podcast – University of Toronto. Updated November 5, 2020. Accessed November 18, 2020.

COVID-19 Webinars – University of Toronto Faculty of Medicine. No date. Accessed November 18, 2020.

Covid-19/Covid-19 webinars – Guidelines International Network. No date. Accessed November 18, 2020. 

 

Telemedicine and virtual care 

Virtual Care Playbook – Canadian Medical Association, The College of Family Physicians, and Royal College of Physicians and Surgeons of Canada. March 30, 2020. Accessed November 18, 2020.

Telemedicine and virtual care guidelines (and other clinical resources for COVID-19) – Royal College of Physicians and Surgeons of Canada. Updated July 6, 2020. Accessed November 18, 2020.

Virtual care is here to stay  – Ontario MD. No date. Accessed November 18, 2020.

Enablers for virtual visits – CADTH – Updated September 4, 2020. Accessed November 18, 2020.

Rapid response to COVID-19 – Canada Health Infoway. No date. Accessed November 18, 2020.

Virtual care guide for patients - Canadian Medical Association, The College of Family Physicians, and Royal College of Physicians and Surgeons of Canada. June 2020. Accessed November 18, 2020.

Virtual Care- Toolkit – Doctors of BC. November 3, 2020. Accessed November 18, 2020.

COVID-19: Virtual Care - College of Physicians & Surgeons of Alberta. Updated May 25, 2020. Accessed November 18, 2020.

 

Ethics and medical-legal resources

Framework for Ethical Decision Making During the Coronavirus Pandemic – Canadian Medical Association. Updated April 1, 2020. Accessed November 18, 2020.

COVID-19 Hub – advice, support, and medical-legal protection during the COVID-19 pandemic – Canadian Medical Protective Association. Updated November 16, 2020. Accessed November 18, 2020.

Ethics – BC Centre for Disease Control. No date, 2020. Accessed November 18, 2020.

Public Health Ethics and COVID-19: Selected Resources – National Collaborating Centre for Healthy Public Policy/ Institut national de santé publique (Québec).  Last updated: October, 2020. Accessed November 18, 2020.

Ethics Resources on the Coronavirus (COVID-19) - collection of articles and reports on ethics related to COVID-19, other coronaviruses and pandemics. – Hastings Center. No date. Accessed November 18, 2020.

 

Patient education resources

COVID-19 Resources and Tools for the public – Canadian Medical Association.  No date. Accessed November 18, 2020.

Questions and answers on COVID-19 – Canadian Medical Association, the College of Family Physicians of Canada and the Royal College of Physicians and Surgeons of Canada. Updated November 10, 2020. Accessed November 18, 2020.

Symptoms checklist: COVID-19, cold and flu – How do they compare? - CanadianHealthcareNetwork.ca - compiled from the Public Health Agency of Canada, the U.S. Centers for Disease Control and the World Health Organization. September 7, 2020. Accessed November 18, 2020.

What you should know about COVID-19 to protect yourself and others  – Centers for Disease Control and Prevention. Updated June 1, 2020. Accessed November 18, 2020.

Prevent the spread of COVID-19 if you are sick   – Centers for Disease Control and Prevention. August 11, 2020. Accessed November 18, 2020.

Coronavirus Disease (COVID-19): Awareness resources (fact sheets and infographics available in many languages) – Public Health Agency of Canada. Updated November 17, 2020. Accessed November 18, 2020.

 

Databases and pre-populated literature searches *

COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv  *

COVID-19 global literature on coronavirus disease - World Health Organization

Cochrane Library - Coronavirus (COVID-19) – evidence relevant to critical care.

Coronavirus disease (COVID‑19) - Epistemonikos foundation L·OVE database.

COVID-19 Live Literature Searches - Australian Library and Information Association.

COVID-19 primer – Powered by Primer (AI) – dashboard for latest research and trending news and articles. 

LitCovid – the US National Library of Medicine’s curated literature hub for tracking up-to-date scientific information about the virus.

GoogleScholar search

Pubmed search

Trip database search (Turning research into practice)

 

Need more information or have a more focused clinical question on coronaviruses or any other clinical topic of interest? Contact the Ask a Librarian team to request a literature search.

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This material is for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice. The opinions stated by the authors are made in a personal capacity and do not necessarily reflect those of the Canadian Medical Association and its subsidiaries including Joule.

 

About the author(s)

Joule’s medical librarians are the professionals behind “Ask a Librarian”, a service for all CMA members looking for clinical search expertise. This experienced team of librarians can support you by searching on your behalf, teaching you effective search strategies or training you to use our clinical resources.

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